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导师姓名:王霞 出生年月:1984.1 职称:副教授 学历(学位):研究生(博士) 导师类别:硕士生导师 行政职务:教研室主任,党支部副书记 招生专业:生物与医药,海洋化学,轻工技术与工程 研究方向:生化与分子生物学 联系方式:15092182150 |
一、个人简介
王霞,女,中共党员,副教授。2018年作为高层次人才入职青岛科技大学,工作至今。国际期刊FISH & SHELLFISH IMMUNOLOGY,ARCHIVES OF GERONTOLOGY AND GERIATRICS的审稿人,国家自然科学基金评议专家,中国橡胶工业协会胶鞋分会专家。
二、研究方向
1.水产动物免疫机理研究;
2.抗菌肽的筛选、功能鉴定及应用;
3.利用斑马鱼为模式生物进行评价;
4.真菌菌丝体生物基材料的制备及应用。
三、教育及工作经历
教育经历:
2012.8-2015.6,中国海洋大学,海洋生物学,获理学博士学位;
2009.8-2012.6,青岛科技大学,发酵工程,获工学硕士学位;
2002.9-2006.6,青岛科技大学,生物工程,获工学学士学位。
工作经历:
2018.1-至今, 9001cc金沙以诚为本;
2015.7-2017.12,中国海洋大学,发育学,博士后;
2006.9-2008.10,山东省鲁南制药集团新时代药业有限公司。
四、个人荣誉与获奖
1.自工作以来多次获评先进个人,其中,2021年和2023年被评为校级先进个人;
2.第四届教学创新比赛获青岛科技大学三等奖(2024.02);
3.第七届“海创杯”科技创新成果交流展暨第十四届“挑战杯”校赛选拔赛——三等奖(2024.01);
4.山东省大学生创新创业项目获省级立项(2023.10);
5.获青岛科技大学毕业生“我最喜爱的老师”荣誉称号(2022.06);
6.青岛科技大学“同心喜迎二十大,铸魂筑梦育新人”师德师风主题征文获三等奖(2022.10);
7.获“建行杯”第五届山东省“互联网+”大学生创新创业大赛银奖(2019.9);
8.互联网+”大学生创新创业大赛青岛科技大学优秀指导老师(2019.9);
9.获中国海洋学会和中国太平洋学会颁发的海洋科学技术奖二等奖(2019.10)。
五、承担的主要科研项目
1.CRIP1与斑马鱼衰老的相关性及作用机制研究 国家自然科学基金青年基金,主持;
2.间歇性节食对贡氏假鳃鳉寿命、衰老标记物和胰岛素/胰岛素样生长因子1信号(Ⅱ)通路的影响 山东省自然科学基金,主持;
3.青岛科技大学人才启动经费,主持;
4.海洋牧场构建关键藻类海带附生菌群落结构对高温的响应规律,参与;
5.文昌鱼VCBP免疫识别和效应功能研究:VCBP类抗体功能探索 国家自然科学基金青年基金,参与;
6.鱼类母源性免疫因子的分离、鉴定及作用机理 国家自然科学基金面上项目,参与。
六、承担的主要教学项目
1.青岛科技大学程思政示范课程—《分子生物学》立项(1/5,2023);
2.山东省社区教育优秀课程立项(2/3,2023);
3.青岛科技大学研究生教育课程思政示范课程立项 (2/8,2022);
4.互联网+背景下研究生生物科学前沿讲座课程思政改革探讨(2/8,2023);
5.基于微生态理论的研究生培养模式改革与实践研究校级-面上(5/5,2023);
6.本科毕业生校级优秀学士论文(1/1,2022);
7.青岛科技大学课程思政示范课程—《生化工程设备》立项(2/3,2021);
8.青岛科技大学课程思政示范课程—《制药生物化学B》立项(3/6,2021);
9.青岛科技大学研究生课程思政示范项目《食品生物工程》立项(4/6,2023);10. 青岛科技大学第二批校级一流本科课程名单《制药生物化学》立项(4/4,2023);
10、制药专业学生基于《制药生物化学》与创新创业能力培养相融合的教学改革立项(5/9,2020);
11、青岛科技大学课程思政教育教学改革试点立项课程—《制药生物化学B》立项(3/6,2018)。
七、教学情况
承担本科课程:《分子生物学》、《生物反应工程》、《生物工程工厂设计》和《生物工程创新实践活动》。参与讲授研究生课程《生物科学前沿讲座》。
八、论文、专著与专利
科研论文:
1. Gong, C.M., He, J., Guo, D.Q., Zhang, L.Q., Shi, .P., Wang, X.*. Identification of zebrafish GIGYF2 presents in egg/embryo as an antibacterial protein. Fish and Shellfish Immunology. 2023 Sep:140:108957.
2. Ren, Y.Q., Wang, C.Q., Wang, H., Chang, Q.Q., Guo, D.Q., Wang, X.*. Identification of zebrafish PLEKHF2 presents in egg/embryos as an antibacterial protein. Fish and Shellfish Immunology. 2022, 127, 925-932.
3. Chen, Y.F., Wang, X., Sui, Q., Chang, G.Z., Sun, X.M., Zhu, L., Chen, B.J., Qu, K.M., Xia, B.. Charge-dependent negative effects of polystyrene nanoplastics on Oryzias melastigma under ocean acidification conditions. Science of The Total Environment. 2023, 161248.
4. Ran, F.F. Wang, X., Li, H.X., Zhang, H.H., Pang, J.H., Wang, Z.P., Li, L.*. High yield of reducing sugar from enzymolysis of cellulose in supercritical carbon dioxide system, Industrial Crops & Products, 2022, 178:14632.
5. Wang, X.*, Ren, Y.Q., Gong, C.M., Chen, Y.F., Ge, X.P., Kong, J., Sun, W.J., Du, X.Y..40S ribosomal protein S18 is a novel maternal peptidoglycan-binding protein that protects embryos of zebrafish from bacterial infections. Dev Comp Immunol. 2021 Dec; 125:104212.
6. Wang, X.D., Li, C.M., Jia, J.H., Xu, T.X., Wang, Y.L., Sun, M.Z., Han, S.H., Wang, X.*, Qiu, L.M.. Regulation of apoptosis by Pacific oyster Crassostrea gigas reveals acclimation strategy to CO2 driven acidification. Ecotoxicology and Environmental Safety. 2021, 217:112235.
7. Ni, S.S., Zhou, Y., Song, L.L., Chen, Y., Wang, X., Du, X.Y., Zhang, S.C.. ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection. Communications biology. 2021, 251:4.
8. Wang, X.*, Ren, Y.Q., Li, J., Ji, Z., Chen, F.S., Wang, X.*. Identification of the 14-3-3 β/α-A protein as a novel maternal peptidoglycan-binding protein that protects embryos of zebrafish against bacterial infections. Dev Comp Immunol. 2020 Sep 12;114:103867.
9. Wang, X.*, Ren, Y.Q., Du, X., Song, L.L, Chen, F.S., Su, F.*. Effects of late-onset dietary intake of salidroside on insulin/insulin-like growth factor-1 (IGF-1) signaling pathway of the annual fish Nothobranchius guentheri. Arch Gerontol Geriatr. 2020 Aug 17;91:104233.
10. Du, X.Y., Zhou, Y., Song, L.I., Wang, X.*, Zhang, S.C.*. Zinc finger protein 365 is a new maternal LPS-binding protein that defends zebrafish embryos against gram-negative bacterial infections. FASEB J. 2018 Feb;32(2):979-994.
11. Wang, X., Du, X.Y., Zhou, Y., Wang, S., Su, F.*, Zhang, S.C.*. Time-dependent effects of late-onset dietary intake of salidroside on lifespan and age-related biomarkers of the annual fish Nothobranchius guentheri. Oncotarget. 2018 Jan 4;9(19):14882-14894.
12. Wang, X., Du, X.Y., Zhou, Y., Wang, S., Su, F.*, Zhang, S.C.*. Intermittent food restriction initiated late in life prolongs lifespan and retards the onset of age-related markers in the annual fish Nothobranchius guentheri. Biogerontology. 2017 Jun;18(3):383-396.
13. Wang, X., Du, X.Y., Li, H.Y.*, Zhang, S.C.*. Identification of the zinc finger protein ZRANB2 as a novel maternal lipopolysaccharide-binding protein that protects embryos of zebrafish against gram-negative bacterial infections. J Biol Chem. 2016 Feb 19;291(8):4019-34.
14. Wang, X., Chang, Q.Y., Wang, Y., Su, F., Zhang, S.C.*. Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway. Rejuvenation Res. 2014 Dec;17(6):507-17.
15. Wang, X., Shang, X.M., Luan, J., ZhangM S.C.*. Identification, expression and function of apolipoprotein E in annual fish Nothobranchius guentheri: implication for an aging marker. Biogerontology. 2014 Jun;15(3):233-43.
16. Song, L.L., Zhou, Y., Ni, S.S., Wang, X., Yuan, J.S., Zhang, Y., Zhang, S.C.. Dietary Intake of β-Glucans Can Prolong Lifespan and Exert an Antioxidant Action on Aged Fish Nothobranchius guentheri. Rejuvenation Res. 2020 Aug;23(4):293-301.
17. Song, L.L. Yuan, J.S., Ni, S.S., Zhou,Y., Wang, X., Chen, Y., Zhang, S.C.. Enhancement of adaptive immune responses of aged mice by dietary intake of β-glucans, with special emphasis on anti-aging activity. Molecular immunology. 2020, 117, 160-167.
18. Zhou, Y., Ni, S.S., Song, L.L., Wang, X., Zhang, Y., Zhang, S.C.. Late-onset administration of GDF11 extends life span and delays development of age-related markers in the annual fish Nothobranchius guentheri. Biogerontology. 2019 Apr;20(2):225-239.
19. Du, X.Y., Wang, X., Wang, S., Zhou, Y., Zhang, Y.*, Zhang, S.C.*. Functional characterization of Vitellogenin_N domain, domain of unknown function 1943, and von Willebrand factor type D domain in vitellogenin of the non-bilaterian coral Euphyllia ancora: Implications for emergence of immune activity of vitellogenin in basal metazoan. Dev Comp Immunol. 2017 Feb;67:485-494.
20. Bai, Y., Liu, S.S., Wang, X., Du, X.Y., Ji, G.D.*, Zhang, S.C.*. Identification of neuroglobin as a novel player in anti-bacterial responses in amphioxus. Dev Comp Immunol. 2017 Dec;77:157-165.
21. Liu, C.S., Wang, X., Feng, W.R., Li, G.R., Su, F., Zhang, S.C.*. Differential expression of aging biomarkers at different life stages of the annual fish Nothobranchius guentheri. Biogerontology. 2012 Oct;13(5):501-10.
教学论文:
1.王霞,李昉,梁成伟,王秀丹,王晓琨,魏曼曼.生物工程专业“分子生物学”教学改革探讨[J].山东化工,2020,49(15);
2.李昉,王霞,顾玉超.产教融合驱动创新思政教学模式.青岛日报,2024.4.20;
3.史振平,王霞,刘全兰,李凤梅.茶在《食品毒理学》教学中的案例应用[J].
福建茶叶,2023(04),106-108;
4.梁成伟,王霞,丛静.“生物化学”课程思政的建设原则与措施[J]. 2023,中国科技期刊数据库;
5.魏曼曼,梁成伟,王秀丹,王霞,丛静.新工科背景下基于OBE理念的生物
化学教学模式的改革与创新[J]. 生命的化学, 2023(02), 311-316.
授权专利:
1、王霞,宿烽,任屹清.一种调节肠道菌群的海参多糖组合物及其制备方法和应用(专利号ZL 2020 10258999.5),授权.